The Vital Role of the Liver

Did you know that our bodies have 78 different organs? But guess what? Only five of them are super important for keeping us alive. These are the heart, one kidney, one lung, the brain, and the liver.

Now, let’s talk about the liver. It’s this big thing inside us, the largest exocrine gland in our body. That means it makes stuff that goes out of our body, unlike other glands that send stuff into our bloodstream. The liver weighs about 1.5 kilograms, and it’s like a busy highway with more than 1500 milliliters of blood zooming through it every minute!

The liver has some really cool jobs. It helps process the nutrients we get from food, makes bile to help digest fat, and it’s like a clean-up crew, getting rid of toxins in our body. Plus, it’s like a storage unit, holding onto important stuff like glycogen and protein.

So, you see, the liver is pretty amazing. It’s like a superhero inside us, doing all these important tasks that keep us healthy and alive.

When we talk about liver function, it’s often linked to certain medications. Like cholesterol-lowering drugs (statins) or antibiotics such as amoxicillin, clindamycin, and erythromycin. Even some dietary supplements and herbs like milk thistle, comfrey, and swallowwort can affect the liver.

Exploring the Effects of CBD on Liver Function

Now, there’s a lot of interest in CBD, and people are curious about its impact on the liver. The liver is pretty good at healing itself, especially from minor damage. It grows new cells almost right away through substances called chalones that help with tissue formation. However, if the liver faces long-term damage, its ability to regenerate diminishes.

So, while the liver can bounce back from small issues, it struggles with big, ongoing damage. That’s why it’s important to be careful of what we put into our bodies. Including medications, supplements, and herbs, and to keep an eye on how they might affect our liver health.

When doctors run tests on your blood in the lab, they check for certain liver enzymes like ALT, AST, GGT, ALP, and bilirubin. If these levels are high, it could mean different things. Sometimes, it’s just a normal thing because of your genes, and it doesn’t really harm your liver. Other times, it might be a response to an infection, or it could show that your liver has been seriously hurt.

But you can help your liver stay healthy by taking milk thistle as a preventive measure. It’s like giving your liver a little boost to keep it in good shape. So, even if your liver is doing okay right now, it’s always a good idea to take care of it!

CBD and Liver

CBD has been found to have many benefits. Such as easing chronic pain, reducing inflammation and anxiety, helping with skin issues and autoimmune diseases. And even supporting sexual health and reproduction. However, when it comes to the liver, there hasn’t been much evidence of a positive effect.

Scientists have done tests on mice to see if CBD could help the liver. But they haven’t found any solid results suggesting that it does. So, while CBD might do wonders for other parts of the body, it doesn’t seem to have much of an impact on liver function based on current research.

In the study, scientists tested CBD on mice in two stages. First, they gave them a dose equivalent to 200 mg of CBD per kilogram of body weight, which is a high dose for humans. After this, the mice’s livers showed signs of increased toxicity.

In the second stage, the mice were given a lower dose of only 50 mg per kilogram of body weight per day. Even at this lower dose, the mice’s livers swelled and showed signs of damage.

These findings suggest that CBD can have harmful effects on the liver, even at lower doses. It’s essential to consider these results when using CBD or any other substance, especially if you have concerns about liver health.

Most experts agree that CBD generally doesn’t harm the liver. The experiments conducted on mice used extremely high doses of CBD. Which when scaled for an average 70 kg person, amounted to 14,000 mg and 3,500 mg respectively. This is way beyond what most people would ever take. For comparison, the typical daily dose for many users is up to 60 mg per day, which is much, much lower.

It’s important to note that while all mammals, including mice and humans, have similar endocannabinoid systems, our bodies and physiology are different. One key difference is the size of our livers. Because of these variations, the study used parameters that didn’t exactly match human conditions. As a result, it’s hard to draw any meaningful conclusions about how CBD affects the human liver based on these experiments.

If you’re using CBD and want to be extra careful with your liver, you can split your dose into two parts: one in the morning and one in the evening. This gives your liver time to process the CBD. As long as you stick to the recommended dosage, the risk of harming your liver is pretty much zero.

However, CBD does have some limitations. People with liver disease, heart issues, low blood pressure, or those who are pregnant or breastfeeding, should avoid using it. It’s essential to be honest with your doctor and consult them before starting CBD. Also, combining CBD with other dietary supplements or certain medications. Like cholesterol drugs or antibiotics, might be too much for your body to handle. So, it’s crucial to be cautious and seek professional advice.

The Issue Lies in the Composition

There aren’t strict regulations governing the exact makeup of cannabis products. So the information on labels might not always be accurate. Even though there are checks in place to catch mistakes, a significant percentage of products can still be found to have errors. For instance, in California in 2018, 80% of tested CBD products had inaccuracies in their ingredients list.

To be absolutely certain about what you’re putting into your body. And to get the most benefits from using CBD without risking harm, including potential liver damage. It’s best to buy products that have been analyzed and certified. This ensures that you’re getting what you expect and can trust the quality of the product.

Final Word

CBD generally has minimal effect on liver function, especially when taken at recommended doses. However, it’s crucial to choose high-quality products with certifications that detail the origin, manufacturing process, and exact ingredients. This ensures that you’re getting a safe and reliable product, reducing any potential risks associated with CBD use. So, while CBD may not pose significant risks to liver health, selecting reputable products is still essential for overall safety and effectiveness.